Sempre Hair Growth System with shampoo, conditioner, hair gowth foam and vitamins

Sempre Proven Results: 100% would incorporate into regimen, 88% noticed improvement in overall hair appearance

Sempre Foam before and after pictures with visibly thicker hair

Sempre Hair Growth Foam Before and After Pictures

Sempre Hair Growth Collection: shampoo, conditioner, hair growth foam and vitamins

Woman washing her hair in the shower with Sempre Hair Growth Shampoo and Conditioner

Sempre Hair Growth Shampoo and Conditioner Botanical Benefits

Sempre Hair Growth Foam Botanical Benefits

Sempre Hair Growth Organonutrients: Proprietary Botanical Blend

Timeline of what to expect with Sempre Hair Growth Products

Cinematic lighting and intro to Sempre Hair Growth Shampoo and Conditioner

Sempre Hair Growth Essentials

Sempre Essentials

The complete Sempre pathway for advanced botanical hair and scalp support.

Includes coordinated cleanse, condition, internal and targeted support steps
Features TR6™ Botanical Technology across a complete pathway

TR6™ Botanical Technology Complete Routine

The complete collection routine. Includes the collection’s essential products in one coordinated pathway.
The complete Sempre pathway. Combines TR6™-powered wash care and targeted support within Origenere’s strongest botanical growth-support collection.
One clear routine. Use each included product as directed to support consistency from step to step.

Sempre Hair Growth Support System

sem·pre /ˈsemˌprā/ — Italian for "always." Because lasting results are built one day at a time.

Sempre is Origenere's most advanced growth-support system, designed for those actively addressing the appearance of thinning hair and seeking a more comprehensive routine.

Powered by TR6™ Botanical Technology, the Sempre System brings together scalp care, strand support, topical care, and daily internal support in one consistent protocol. The shampoo and conditioner help refresh the scalp and support stronger-feeling, fuller-looking hair. The topical foam provides targeted scalp support, while the daily hair-support vitamins help complement the routine from within.

The Sempre System has been clinically demonstrated to support the appearance of thicker, denser hair with consistent use.

Where Naturale offers a clean botanical foundation for daily maintenance, Sempre is the stronger pathway for those ready for Origenere's most complete growth-support routine.

Use consistently for at least 3 months before evaluating visible changes, as hair appearance depends on the natural hair growth cycle. Individual results may vary.

Best for

Best for users who want Origenere’s complete Sempre pathway, with coordinated wash care and targeted botanical support in one routine.

The complete Sempre routine for advanced botanical growth support.

Prefer a Simpler Starting Point?

Choose a Sempre duo or individual product if you prefer fewer steps. Compare another collection if advanced botanical growth support is not your primary goal.

Choose a duo or individual product for a simpler starting point.

Shop Sempre Options Find My Routine

TR6™ Botanical Technology

Advanced Botanical Support, Rooted in Hair Restoration Research

TR6™ is Origenere’s advanced botanical technology, developed from the research heritage of AlviArmani, an international hair restoration company. Rooted in decades of hair and scalp insight and evaluated through multiple clinical study series, TR6™ brings a bioactive botanical approach to Origenere’s most intensive growth-support pathway.

AlviArmani Research Heritage

Developed from the research heritage of AlviArmani, an international hair restoration company, TR6™ brings decades of hair and scalp insight into Origenere’s botanical care system.

Multiple Clinical Series

TR6™ has been evaluated through multiple clinical study series as part of its ongoing development and refinement.

Bioactive Follicle Support

A bioactive botanical approach designed to support the scalp environment and the appearance of fuller-looking, healthier-feeling hair.

TR6 Botanical Technology by Origenere with bioactive botanical, scalp, and follicle support visuals

Swipe to compare pathways

Current Complete Routine

Sempre

Origenere’s strongest growth-support pathway, featuring TR6™ Botanical Technology.

Advanced botanical support
Best for growth-support routines
Hair + scalp focused

View Sempre Options

Current Complete Routine

Naturale

A clean botanical foundation for users starting or simplifying their hair support routine.

Botanical-first foundation
Moderate growth support
Simple routine starting point

Shop Naturale

Current Complete Routine

Buongiorno

A scalp vitality pathway focused on freshness, comfort, and a healthy-feeling scalp environment.

Scalp-focused support
Freshness and comfort
Rosemary-focused care

Shop Buongiorno

Current Complete Routine

La Rosa

A DHT-blocker-free strand support pathway for softness, resilience, and fragility support.

DHT-blocker-free support
Softness and resilience
Healthier-looking strands

Shop La Rosa

Formula Focus

Complete advanced botanical pathway

The Sempre Essentials Package combines complementary TR6™-powered products across cleanse, condition, and targeted support steps.

Featured ingredients

Confidential.

TR6™ Botanical Technology

TR6™ is a proprietary botanical complex developed by the AlviArmani Research Institute through more than two decades of in-house bench research, ingredient screening, and procedural field observations. The formulation incorporates plant-derived bioactives selected for their antioxidant, anti-inflammatory, and scalp-supportive properties. Internal laboratory testing and clinical-use evaluations have guided the refinement of TR6™, which is integrated into AlviArmani operative solutions and Origenere® topical formulations as part of a comprehensive approach to scalp and follicular wellness.

Hair Growth Post-Transplant Recovery Graft Survival and Retention Scalp Inflammation Telogen Effluvium Support Density and Thickness

Good to know: Topical botanical complex; patch test before use. For pregnancy, breastfeeding, pre-pubescent use, do not use. Avoid eyes and broken skin. Discontinue if irritation occurs.

Miracle Tree, Drumstick Tree, Horseradish Tree

Moringa

Moringa oleifera

A nutrient-rich “Miracle Tree” that nourishes, strengthens, and protects hair strands. Its vitamins, antioxidants, amino acids, and fatty acids moisturize the scalp, reduce dandruff, and add shine, making it suitable for all hair types, including color-treated and chemically-treated hair.

Hair Growth Scalp Hydration Strengthening Shine Antioxidant Protection Super Food

Good to know: Well Tolerated. Avoid Root and Bark. Avoid Large Quantities. Avoid Use During Pregnancy and Breast Feeding.

Soldier's Wound Wort

Yarrow

Achillea Millefolium

A soothing herb that improves scalp circulation, reduces dandruff, and counter DHT to promote stronger hair growth, while also calming inflammation and protecting against oxidative stress. Modern research highlights its rejuvenating, antimicrobial, and wound-healing properties, making it a powerful natural ingredient in haircare and skincare formulations.

Hair Growth Dandruff Anti-Inflammation Skin Rejuvenation

Good to know: People with allergies to Asteraceae family may have allergic reaction. Powerful hormone modulators so don't use during pregnancy. Stop taking 2 weeks prior to surgery for bleeding risks.

Coltsfoot; Coughwort; Foalsfoot

Coltsfoot

Tussilago farfara

A soothing botanical traditionally used to calm an irritated scalp and reduce flaking. Rich in soothing mucilage, flavonoids, zinc, and silica, coltsfoot helps support the scalp barrier, ease itch, and improve hair softness and shine.

Dandruff Scalp Irritation Scalp Balance Hydration Shine

Good to know: Patch test on sensitive skin. Do not use during pregnancy or breast feeding.

Bamboo extract, Bamboo leaf extract, Bamboo silica

Bamboo Silica

Bambusa vulgaris

Bamboo extract is one of the richest natural sources of organic silica (up to 70%). It strengthens hair strands, boosts scalp circulation, and reinforces keratin and collagen for healthier hair, skin, and nails. Bamboo silica reduces breakage, supports elasticity, and enhances shine, making it a full-spectrum beauty botanical.

Hair Loss Breakage Nail Strength Skin Elasticity Scalp Circulation Collagen Support

Good to know: Generally well tolerated; may cause mild digestive upset if taken on an empty stomach. Rare adverse reactions at very high doses. Consult healthcare provider before use in pregnancy or if on medications.

Indian Winter Cherry, Indian Ginseng

Ashwagandha

Withania Somnifera

A cornerstone of Ayurvedic medicine, is an adaptogenic botanical that reduces cortisol, improves scalp circulation, and protects follicles with powerful antioxidants. Its withanolide-rich profile helps promote hair growth, reduce stress-related shedding, and enhance texture and shine while supporting overall scalp health.

Stress-Related Hair Loss Hair Growth Premature Graying Scalp Inflammation Breakage Anxiolytic Adaptogen

Good to know: Generally safe for healthy adults when used as directed. Avoid in pregnancy and breastfeeding due to potential hormonal activity. Possible mild side effects include stomach upset or drowsiness. Consult a healthcare provider before supplement use, especially if taking thyroid, sedative, or blood pressure medications.

Creeping Palm, Plant of Life

Saw Palmetto

Serenoa repens

Botanical DHT-blocker that helps slow androgenetic alopecia by inhibiting 5-alpha-reductase. Rich in fatty acids, phytosterols, and flavonoids, it reduces inflammation, supports scalp health, and strengthens follicles. Its topical and oral forms have been studied for hair regrowth with generally mild side effects.

Hair Growth Excess Sebum Dandruff BPH Environmental follicle stress

Good to know: Generally well tolerated. Oral forms may cause mild GI symptoms (constipation, nausea). Rare hot flashes in premenopausal women due to antiandrogenic effects. Topical use may cause scalp irritation. Avoid use in pregnancy/breastfeeding due to hormonal activity.

Pepitas

Pumpkin Seed

Cucurbita pepo

Supports hair growth and scalp balance through a synergy of phytosterols, essential fatty acids, zinc, and antioxidants. By moderating 5-alpha-reductase and DHT signaling, it helps reduce shedding, while omega-6/omega-9 lipids, γ-tocopherol, and phenolics fortify the scalp barrier, add shine, and combat oxidative stress. Clinical data (e.g., a 24-week RCT) report ~40% hair count gains with oral pumpkin seed oil versus ~10% with placebo.

Hair Growth Dandruff Hair Softening Protection Against Oxidative Stress

Good to know: Generally well-tolerated. Oral use may cause mild GI upset or pruritus in sensitive individuals. Due to mild anticoagulant potential, consult a clinician if using blood thinners. Discontinue if scalp irritation occurs with topical use. Because of hormone-modulating activity, avoid during pregnancy/breastfeeding unless medically advised.

Red Cinchona; Peruvian Bark; Jesuit’s Bark; Quina

Cinchona Bark

Cinchona Succirubra

Rich in quinoline alkaloids—chiefly quinine and cinchonine—that support scalp microcirculation, calm inflammation, and help maintain a clean, balanced scalp microbiome. In vitro and preclinical data suggest Wnt/β-catenin pathway activation and VEGF-linked perfusion improvements, creating a follicle-friendly environment that may reduce shedding and promote thicker-looking growth. Its antimicrobial and antioxidant profile also helps address dandruff and buildup while protecting against oxidative stress.

Hair Growth Dandruff Seborrheic Scalp Oily Scalp Scalp Microciculation Optimization

Good to know: Patch test before use; alkaloid-rich extracts can cause irritation in sensitive skin. Avoid use during pregnancy or breastfeeding, and consult a clinician if taking interacting medications (e.g., antiarrhythmics, anticoagulants) or with tinnitus/arrhythmia history. Excess or systemic exposure to quinine can cause “cinchonism” (e.g., ringing in ears, dizziness, nausea, visual changes). Discontinue if irritation occurs.

Blue-Green Algae

Spirulina

Arthrospira platensis

A microscopic blue-green algae. Rich in proteins, amino acids, iron, B vitamins, and antioxidant pigments like phycocyanin. Traditionally used by Aztec and African cultures as a superfood, spirulina is now recognized for supporting keratin synthesis, scalp circulation, and antioxidant defense. It strengthens hair shafts, reduces shedding, and promotes long-term scalp health.

Hair Growth Seasonal Shedding Scalp Inflammation Oxidative Stress Nutrient Deficiency

Good to know: Generally safe when sourced from high-quality, tested suppliers. Risk of contamination with heavy metals or microcystins if unregulated. Avoid in patients with phenylketonuria (PKU) or autoimmune conditions without medical guidance. Always patch test for topical use. Consult with healthcare provider if pregnant or breastfeeding.

Sea Kelp; Giant Kelp; Kombu; Wakame

Kelp

Macrocystis pyrifera; Laminaria spp.; Ascophyllum nodosum; Undaria pinnatifida

A nutrient-dense brown seaweed, is rich in iodine, amino acids, trace minerals, and antioxidants. Traditionally used in Asian and Scandinavian medicine to support scalp and hair vitality, kelp strengthens keratin, regulates thyroid hormones, and protects follicles from oxidative stress. Its unique compounds—fucoidans, phlorotannins, and alginates—calm the scalp, hydrate, and defend against hair thinning, making kelp a natural superfood for hair and scalp care.

Nutrient Deficiency Hair Growth Scalp Inflammation Oxidative Stress

Good to know: Kelp is safe when responsibly sourced and consumed in moderation. Excess iodine intake may affect thyroid function, blood pressure, or interact with thyroid medications. Avoid “mega-dose” supplements unless under medical supervision. Always patch test topicals. Avoid during pregnancy because of high iodine content.

Field Horsetail

Horsetail

Equisetum arvense

A traditional herbal remedy valued for its silica, antioxidants, and minerals that strengthen hair, support follicle density, and promote scalp circulation. Its historic and modern uses include teas, rinses, and supplements for hair growth, wound healing, and urinary tract support.

Hair Growth Breakage Brittle Nails Wound Healing Scalp Irritation

Good to know: Generally safe in moderate use. Avoid high or prolonged doses due to potential kidney effects and potassium depletion. Rare cases of liver toxicity reported at high doses. Can interact with diuretics, lithium, and some medications. Always consult a provider before supplement use, especially with kidney disease. Not considered safe during pregnancy.

Ingredient lists by product

Please refer to each included product’s packaging for its current full ingredient list.

How to use the complete routine

Begin with the included shampoo on wet hair and scalp, then rinse thoroughly. Follow with the included conditioner through the lengths and ends. Apply any included tonic, foam, leave-in, or other targeted product as directed on its individual label. Take any included supplement only as directed on its packaging.

Good to know

Each product in this package has its own ingredient list and usage instructions. Review the individual packaging for the most current information.

Individual results may vary. Origenere products are cosmetic hair and scalp care products and are not intended to diagnose, treat, cure, or prevent disease.

Routine Guidance

Not sure if Sempre is the right fit?

Sempre is best for users seeking Origenere’s advanced botanical growth-support pathway featuring TR6™ Botanical Technology.

Find My Routine

Is this product right for a growth-support routine?

Sempre is Origenere’s most advanced growth-support collection. This product is designed to support hair and scalp care goals as part of an advanced growth-support routine. Uses TR6 Technology created by AlviArmani Hair Research.

How do I use the complete Sempre routine?

Begin with the Sempre Shampoo on wet hair and scalp, massage gently, and rinse thoroughly. Follow with the Sempre Conditioner through the lengths and ends, then rinse. Massage foam into scalp nightly. Two Sempre Vitamin Capsules daily for internal support.

Can I use this with other Origenere products?

Yes. For a more complete Sempre routine, pair this product with complementary Sempre products depending on your hair and scalp care goals.

Which Origenere collection should I choose?

Choose Sempre if your priority is Origenere’s most advanced botanical growth-support pathway featuring TR6™ Botanical Technology. If you are unsure, use Find My Routine to choose the pathway that best fits your hair and scalp goals.

What changes might I notice with consistent use?

Hair and scalp support routines require consistency. Some users may notice changes in softness, freshness, manageability, or overall hair feel earlier, while fuller-looking results may take longer.

Is this a treatment for hair loss?

No. Origenere products are cosmetic hair and scalp care products designed to support healthier-feeling hair and scalp routines. Our ingredient formulations are backed by science and our in house research team. They are not intended to diagnose, treat, cure, or prevent disease.

Complete Routine

Ready to begin the complete Sempre routine?

Add the Sempre Essentials Package for coordinated cleanse, condition, and targeted support within Origenere’s strongest botanical growth-support pathway.

Complete collection pathway