Excellent for sensitive scalps and curly hair.
Very gentle and neutral on the scalp while effectively reducing frizz.
Our top pick for “best hair growth shampoo,” engineered with TR6™ Botanical Complex to support thicker-looking hair.
Powered by the exclusive TR6™ Botanical Complex, Sempre™ is physician-developed to support thicker-looking hair, reduce shedding, and elevate scalp health.
"Gentle on my sensitive scalp and curls — fuller, softer hair in weeks." — Verified Customer
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Sempre’s physician-developed TR6™ Botanical Complex works across multiple pathways to create a healthy scalp environment and support thicker-looking hair.
Helps maintain a longer growth window so more follicles remain in the anagen phase.
Botanicals associated with calming DHT-linked signaling on the scalp surface; gentle for daily use.
Non-stripping surfactants and targeted actives support a balanced microbiome and cleaner follicles.
Antioxidants and soothing agents help reduce environmental stress signals that can impact shedding.
Conditioning co-actives improve cuticle smoothness and feel, supporting less breakage.
TR6™ targets multiple pathways tied to hair health and shedding. Consistent use supports a healthier scalp environment and visibly fuller-looking hair in 8–12 weeks.
Cleaner scalp feel, lighter roots, better day-two hair.
Less breakage; strands feel stronger and smoother.
Fuller-looking hair as shedding normalizes and density look improves.
Pair Sempre™ Shampoo’s external botanical support with Sempre Organonutrients to nourish from within.
Join thousands using Sempre™ for a cleaner scalp feel, stronger strands, and visibly fuller-looking hair with consistent use.
 
         
      Most shampoos cleanse. Sempre™ goes further with a clinical, multi-pathway botanical approach specifically crafted for hair-growth support.
Most users report fuller-looking, stronger-feeling hair within 8–12 weeks of consistent use (wash cadence 3–5x/week).
Yes. The formula is sulfate-free and designed to cleanse without stripping, supporting comfort and barrier integrity.
Sempre’s TR6™ complex features multi-pathway botanicals; see ingredients in our Ingredient Hub.
We blend in smaller lots to better control temperature, mixing, and hold times. This helps maintain botanical freshness and consistent texture/feel from batch to batch.
Absolutely. Sempre™ is suitable for all hair types and is used by men and women.
Pair with Sempre Foam and Organonutrients for best results.
We offer a 30-day money-back guarantee. If you don’t love it, return it within 30 days.
Some botanicals perform better from specific regions or suppliers with reliable profiles. Importing select actives helps us maintain identity, purity, and consistency.
Experience the Sempre™ difference — science-forward care, luxurious feel, visible results.
 
          Support follicles externally with Shampoo and nourish from within with Organonutrients.
Learn MoreVery gentle and neutral on the scalp while effectively reducing frizz.
Luxury feel. Doesn’t weigh down fine hair — softer, shinier, healthier.
I have very oily hair and this is the best — feels fresh; safe for daily use.
~3 months in — looks healthier and frizz is down. Keeping it in my routine.
4 months of growth with shampoo + vitamins. Hair feels super healthy.
Fine hair feels bouncy and shiny — and fuller overall.
Texture makes you want to linger — hair looks healthier after first use.
Using 4x/week with vitamins. Less shedding and better root volume.