Best Hair Growth Shampoo for Thinning Hair & Hair Loss Support
Our top pick for “best shampoo for thinning and hair loss,” engineered with TR6™ Botanical Complex to support fuller-looking hair.
Powered by the exclusive TR6™ Botanical Complex, Sempre™ is physician-developed to support thinning hair, early pattern hair loss, and stress-related shedding while elevating scalp health.
Want extra support? You can add Sempre™ Foam to your routine later on this page.
"Gentle on my sensitive scalp and curls — fuller, softer hair in weeks." — Verified Customer
30-day returns · Fast shipping
- Multi-pathway actives vs single-ingredient shampoos
- Barrier-friendly cleanse vs harsh sulfates
- Physician-developed with 30-day guarantee
How Sempre™ Supports the Hair-Growth Cycle
Sempre’s physician-developed TR6™ Botanical Complex works across multiple pathways to create a healthy scalp environment, support thinning hair, and improve density look over time.
TR6™ Anagen Support (Growth Phase)
Helps maintain a longer growth window so more follicles remain in the anagen phase.
Miniaturization Modulation
Botanicals associated with calming DHT-linked signaling on the scalp surface; gentle for daily use.
Microbiome & Sebum Balance
Non-stripping surfactants and targeted actives support a balanced microbiome and cleaner follicles.
Calm, Resilient Scalp
Antioxidants and soothing agents help reduce environmental stress signals that can impact shedding.
Strand Strength & Breakage
Conditioning co-actives improve cuticle smoothness and feel, supporting less breakage.
Clinically Minded, Botanically Advanced
TR6™ targets multiple pathways tied to hair health and shedding. Consistent use supports a healthier scalp environment and visibly fuller-looking hair in 8–12 weeks.
What to Expect (Consistency Wins)
Week 1
Cleaner scalp feel, lighter roots, better day-two hair.
Week 4
Less breakage; strands feel stronger and smoother.
Weeks 8–12
Fuller-looking hair as shedding normalizes and density look improves.
Internal + External Support for Visible Results
Pair Sempre™ Shampoo’s external botanical support with Sempre Organonutrients to nourish from within.
Boost Your Results with Sempre™ Foam
Layer the leave-in Sempre™ Foam on top of your shampoo routine to extend contact time with targeted botanicals and support a fuller-looking result.
Leave‑In Contact
Applies to dry scalp and absorbs quickly for targeted, longer contact with key botanicals.
Pairs with Shampoo
Use shampoo 3–5×/week and Foam daily for external support across wash days.
Lightweight Finish
Non‑greasy, style‑friendly texture designed for all hair types.
Real People. Real Routines.
Join thousands using Sempre™ for a cleaner scalp feel, stronger strands, and visibly fuller-looking hair with consistent use.
Designed for Growth Support — Not Just Shine
Most shampoos cleanse. Sempre™ goes further with a clinical, multi-pathway botanical approach specifically crafted for hair-growth support.
Frequently Asked Questions
How soon will I see results?
Most users report fuller-looking, stronger-feeling hair within 8–12 weeks of consistent use (wash cadence 3–5x/week).
Is this a good anti–hair loss shampoo for thinning hair?
Sempre™ was formulated specifically for thinning hair and increased shedding. While no cosmetic shampoo can claim to cure hair loss, its TR6™ Botanical Complex, sulfate-free base, and scalp-first design make it an excellent option if you’re looking for a stimulating shampoo that supports hair growth and density look.
Is Sempre™ safe for sensitive scalps?
Yes. The formula is sulfate-free and designed to cleanse without stripping, supporting comfort and barrier integrity.
Does Sempre™ include DHT-modulating botanicals?
Sempre’s TR6™ complex features multi-pathway botanicals; see ingredients in our Ingredient Hub.
What does “micro-batched” mean?
We blend in smaller lots to better control temperature, mixing, and hold times. This helps maintain botanical freshness and consistent texture/feel from batch to batch.
Can both men and women use it?
Absolutely. Sempre™ is suitable for all hair types and is used by men and women.
How should I complete the routine?
Pair with Sempre Foam and Organonutrients for best results.
What if it’s not for me?
We offer a 30-day money-back guarantee. If you don’t love it, return it within 30 days.
Why import certain ingredients?
Some botanicals perform better from specific regions or suppliers with reliable profiles. Importing select actives helps us maintain identity, purity, and consistency.
Transform Your Hair with the Best Shampoo for Growth
Experience the Sempre™ difference — science-forward care, luxurious feel, visible results.
Complete Your Routine (Internal + External)
Support follicles externally with Shampoo and nourish from within with Organonutrients.
Learn More