Excellent for sensitive scalps and curly hair.
Feels very gentle and neutral on the scalp while controlling frizz and enhancing curl definition. No irritation — curls stay smooth and manageable.
Our top pick for “best hair growth shampoo,” engineered with TR6™ Botanical Complex to support thicker-looking hair.
Powered by the exclusive TR6™ Botanical Complex, Sempre™ is physician-developed to support thicker-looking hair, reduce shedding, and elevate scalp health.
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Sempre’s physician-developed TR6™ Botanical Complex works across multiple pathways to create a healthy scalp environment and support thicker-looking hair.
Helps maintain a longer growth window so more follicles remain in the anagen phase at any given time.
TR6™ features botanicals associated with calming DHT-linked signaling on the scalp surface while remaining gentle for daily use.
Non-stripping surfactants and targeted actives support a balanced scalp microbiome and cleaner follicles for better topical performance.
Botanical antioxidants and soothing agents help reduce environmental stress signals that can impact shedding and comfort.
Conditioning co-actives improve cuticle smoothness and tensile feel, supporting less breakage so hair looks fuller over time.
Pairs with Sempre™ Foam and Organonutrients for comprehensive support.
TR6™ targets multiple pathways tied to hair health and shedding. Consistent use supports a healthier scalp environment and visibly fuller-looking hair in 8–12 weeks.
We import select botanicals for their consistency and profile, then blend Sempre™ in small, micro-batches to protect potency and ensure a fresh, high-quality finish.
Targeted actives (e.g., rosemary, saw palmetto) are sourced from trusted suppliers for verified identity and purity.
Smaller batch sizes reduce heat/time exposure, helping preserve aroma, color, and functional integrity of botanicals.
Each batch is checked for appearance, pH, viscosity, and stability so what you get is consistent, bottle to bottle.
Hair growth is influenced by scalp environment and internal nutrient status. Pair Sempre™ Shampoo’s external, multi-pathway botanical support with Sempre Organonutrients to nourish from within.
Join thousands using Sempre™ for a cleaner scalp feel, stronger strands, and visibly fuller-looking hair with consistent use.
Most shampoos cleanse. Sempre™ goes further with a clinical, multi-pathway botanical approach specifically crafted for hair-growth support.
Most users report fuller-looking, stronger-feeling hair within 8–12 weeks of consistent use (wash cadence 3–5x/week).
Yes. The formula is sulfate-free and designed to cleanse without stripping, supporting comfort and barrier integrity.
Sempre’s TR6™ complex features multi-pathway botanicals; see ingredients in our Ingredient Hub.
We blend in smaller lots to better control temperature, mixing, and hold times. This helps maintain botanical freshness and consistent texture/feel from batch to batch.
Absolutely. Sempre™ is suitable for all hair types and is used by men and women.
Pair with Sempre Foam and Organonutrients for best results.
We offer a 30-day money-back guarantee. If you don’t love it, return it within 30 days.
Some botanicals perform better from specific regions or suppliers with reliable profiles. Importing select actives helps us maintain identity, purity, and consistency.
Experience the Sempre™ difference — science-forward care, luxurious feel, visible results.
Support follicles externally with Shampoo and nourish from within with Organonutrients.
Learn MoreFeels very gentle and neutral on the scalp while controlling frizz and enhancing curl definition. No irritation — curls stay smooth and manageable.
You can feel the luxury. I have baby-fine hair and it doesn’t weigh it down — hair is soft, shiny, and healthier. It’s the only shampoo I use now.
I have very oily hair and this is the best — I feel so fresh after use. Hair feels clean and I can use it every day.
After ~3 months with Sempre my hair looks much healthier and frizz is down. I’m definitely keeping it in my routine — worth it 👍
4 months of growth using the shampoo + conditioner (+ vitamins). Hair feels super healthy and soft. Highly recommend.