Randomized Trial (16 Weeks)
Standardized saw palmetto oil (oral + topical) was associated with reduced hair fall and improvements in growth parameters in adults with pattern hair loss over 16 weeks vs placebo.
Human • 16 weeks • RCT
The Science
Naturale — Saw Palmetto
A purity-first system designed for sensitive scalps and early thinning. Naturale centers on saw palmetto (Serenoa repens)—a botanical known for supporting healthy DHT balance and scalp comfort.
Mechanism of Action
How Saw Palmetto Supports Hair
- 5α-reductase modulation: Liposterolic actives in saw palmetto help maintain healthy conversion of testosterone to DHT at the scalp surface.
- Scalp comfort: Gentle, fragrance-free Naturale bases are designed for sensitive, eczema-prone skin.
- Daily-use system: Shampoo & Conditioner prep the scalp, Naturale Tonic provides leave-on contact, and Styling Cream finishes without occlusive residues.
Fragrance-free • Dermatologist-minded bases • Color-safe
System Design
Formulation & Dosing Rationale
- Rinse + Leave-On pairing: Cleansing phases decongest; the Tonic maintains contact time for consistent scalp exposure.
- Sensitive-first: Purity formulas avoid sulfates, parabens, phthalates, and silicones to reduce barrier disruption.
- Routine: Use Shampoo/Conditioner 3–5× weekly; apply Tonic once daily on clean scalp; finish with Styling Cream as desired.
Need help choosing?
Not sure if Naturale is the best fit? Get a personalized routine based on scalp type and goals.
Want the deep dive on saw palmetto and other actives? Visit the Ingredient Hub (A–Z) →
Recommended Reading
Why Naturale Is Our Pick for Thinning Hair
Looking for a gentle, DHT-aware approach? This guide explains how the Naturale system was built for sensitive scalps and early thinning.
Compare Growth Strength
Qualitative guide across collections
Sempre
Clinical-intensity support (TR6™) for advanced thinning & visible regrowth aesthetics.
Naturale
Moderate strength — DHT-aware, gentle for sensitive scalps.
Buongiorno
Moderate strength — daily scalp vitality & refresh.
La Rosa
Light strength — rose-infused care focused on scalp comfort.
This meter is a qualitative guide for comparing collection intensity levels; individual results vary. For a tailored routine, try the Regimen Finder.
Key Evidence
What the Research Suggests
Topical Saw Palmetto (Clinical)
Clinical data on topical Serenoa repens show signals for improved hair parameters with favorable tolerability profiles in androgen-related hair thinning.
Human • Topical • Clinical
Mechanistic & Preclinical
Liposterolic extracts of Serenoa repens supported hair cell growth and follicle signaling pathways in experimental models, clarifying potential anti-androgen and pro-growth mechanisms.
Mechanism • In vitro
Note: Ingredients support cosmetic appearance and scalp comfort; individual results vary. Consult your clinician for diagnosis and treatment options.
Safety
Who Naturale is For
- Those seeking a fragrance-free, pigment-free routine for sensitive or eczema-prone skin.
- Early thinning or shedding where a gentle, DHT-aware approach is preferred.
- Pairs well with consultation from your clinician; discontinue if irritation occurs.
Quality
Testing & Standards
- Formulas avoid sulfates, parabens, phthalates, and silicones.
- Dermatologist-minded bases; routine stability, micro, and heavy-metal testing per supplier standards.
- Ingredient selection emphasizes standardized botanical extracts and traceability.
FAQs
Science FAQs — Naturale
Is saw palmetto safe for daily topical use?
Topical use is generally well-tolerated; stop use if irritation occurs. People who are pregnant, nursing, or on hormone-related therapies should consult their clinician.
How long until I notice benefits?
Scalp comfort can be immediate; cosmetic improvements in look and feel typically take consistent daily use over several weeks. Individual results vary.
Can Naturale be layered with the Sempre line?
Yes. Many begin with Naturale for scalp harmony, then transition or alternate with Sempre for higher-intensity growth support, per clinician guidance.
Does Naturale contain fragrance?
No—Naturale is formulated without added fragrance or pigment to support sensitive skin routines.
Which line should I choose?
Start with Compare Collections to see intensity and ingredient differences, or use the Regimen Finder for a tailored routine.
Ready to build a sensitive-first routine?
Explore the full Naturale Purity Collection or compare collections to find your ideal routine intensity.